Jack Hearn

2024

Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus

Mugenzi, L. M. J., Tekoh, T. A., Ntadoun, S. T., Chi, A. D., Gadji, M., Menze, B. D., Tchouakui, M., Irving, H., Wondji, M. J., Weedall, G. D., Hearn, J. & Wondji, C. S., 29 Jul 2024, (First published) In: PLoS Genetics. 20, 7, e1011344.

Research output: Contribution to journal › Article › peer-review

Open Access

File

5 Downloads (Pure)

Exploring the molecular mechanisms of increased intensity of pyrethroid resistance in Central African population of a major malaria vector Anopheles coluzzii

Fadel, A. N., Ibrahim, S. S., Sandeu, M. M., Tatsinkou, C. G. M., Menze, B. D., Irving, H., Hearn, J., Nagi, S. C., Weedall, G. D., Terence, E., Tchapga, W., Wanji, S. & Wondji, C. S., Feb 2024, In: Evolutionary Applications. 17, 2, p. e13641 e13641.

Research output: Contribution to journal › Article › peer-review

Open Access

File

22 Downloads (Pure)

Network structure and taxonomic composition of tritrophic communities of Fagaceae, cynipid gallwasps and parasitoids in Sichuan, China

Fang, Z., Tang, C., Sinclair, F., Csóka, G., Hearn, J., McCormack, K., Melika, G., Mikolajczak, K. M., Nicholls, J. A., Nieves‐Aldrey, J., Notton, D. G., Radosevic, S., Bailey, R. I., Reiss, A., Zhang, Y. M., Zhu, Y., Fang, S., Schönrogge, K. & Stone, G. N., 16 Jul 2024, (First published) In: Insect Conservation and Diversity.

Research output: Contribution to journal › Article › peer-review

Open Access

File

9 Downloads (Pure)

Overexpression and nonsynonymous mutations of UDP-glycosyltransferases are potentially associated with pyrethroid resistance in Anopheles funestus

Al-Yazeedi, T., Muhammad, A., Irving, H., Ahn, S. J., Hearn, J. & Wondji, C. S., Mar 2024, In: Genomics. 116, 2, 110798.

Research output: Contribution to journal › Article › peer-review

Open Access

File

1 Citation (Scopus)

22 Downloads (Pure)

Phylogenomic analysis of protein-coding genes resolves complex gall wasp relationships

Hearn, J., Gobbo, E., Nieves-Aldrey, J. L., Branca, A., Nicholls, J. A., Koutsovoulos, G., Lartillot, N., Stone, G. N. & Ronquist, F., Jan 2024, In: Systematic Entomology. 49, 1, p. 110-137 28 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

9 Citations (Scopus)

13 Downloads (Pure)

2023

Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii

Ibrahim, S. S., Muhammad, A., Hearn, J., Weedall, G. D., Nagi, S. C., Mukhtar, M. M., Fadel, A. N., Mugenzi, L. J., Patterson, E. I., Irving, H. & Wondji, C. S., 24 May 2023, (First published) In: BMC Biology. 21, 1, p. 125 125.

Research output: Contribution to journal › Article › peer-review

Open Access

File

13 Citations (Scopus)

33 Downloads (Pure)

The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus

Mugenzi, L. M. J., A Tekoh, T., S Ibrahim, S., Muhammad, A., Kouamo, M., Wondji, M. J., Irving, H., Hearn, J. & Wondji, C. S., 27 Mar 2023, (First published) In: PLoS Genetics. 19, 3, e1010678.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

28 Downloads (Pure)

2022

A novel, magnetic bead-based extraction method for the isolation of antimicrobial resistance genes with a case study in river water in Malawi

Byrne, R. L., Cocker, D., Alyayyoussi, G., Mphasa, M., Charles, M., Mandula, T., Williams, C. T., Rigby, J., Hearn, J., Feasey, N., Adams, E. R. & Edwards, T., 1 Nov 2022, (First published) In: Journal of Applied Microbiology. 133, 5, p. 3191-3200 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Daphnia magna egg piRNA cluster expression profiles change as mothers age

Hearn, J. & Little, T. J., 8 Jun 2022, (First published) In: BMC Genomics. 23, 1, 429.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Gene Conversion Explains Elevated Diversity in the Immunity Modulating APL1 Gene of the Malaria Vector Anopheles funestus

Hearn, J., Riveron, J. M., Irving, H., Weedall, G. D. & Wondji, C. S., 20 Jun 2022, (First published) In: Genes. 13, 6, 1102.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle

Wheelhouse, N., Hearn, J., Livingstone, M., Flockhart, A., Dagleish, M. & Longbottom, D., Apr 2022, In: Journal of Applied Microbiology. 132, 4, p. 2642-2648 7 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Multi-omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa

Hearn, J., Djoko Tagne, C. S., Ibrahim, S. S., Tene-Fossog, B., Mugenzi, L. M. J., Irving, H., Riveron, J. M., Weedall, G. D. & Wondji, C. S., Jul 2022, In: Molecular Ecology. 31, 13, p. 3642-3657 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Citations (Scopus)

Pyrethroid resistance in the New World malaria vector Anopheles albimanus is mediated by cytochrome P450 CYP6P5

Kusimo, M. O., Mackenzie-Impoinvil, L., Ibrahim, S. S., Muhammad, A., Irving, H., Hearn, J., Lenhart, A. E. & Wondji, C. S., May 2022, In: Pesticide Biochemistry and Physiology. 183, 105061.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

RNAseq-based gene expression profiling of the Anopheles funestus pyrethroid-resistant strain FUMOZ highlights the predominant role of the duplicated CYP6P9a/b cytochrome P450s

Wondji, C. S., Hearn, J., Irving, H., Wondji, M. J. & Weedall, G., 4 Jan 2022, In: G3: Genes, Genomes, Genetics. 12, 1, jkab352.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Citations (Scopus)

2021

DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna

Hearn, J., Plenderleith, F. & Little, T. J., 6 Jan 2021, In: Epigenetics and Chromatin. 14, 1, 4.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Citations (Scopus)

Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa

Kouamo, M. F. M., Ibrahim, S. S., Hearn, J., Riveron, J. M., Kusimo, M., Tchouakui, M., Ebai, T., Tchapga, W., Wondji, M. J., Irving, H., Boudjeko, T., Boyom, F. F. & Wondji, C. S., 13 Apr 2021, In: Genes. 12, 4, 561.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Citations (Scopus)

The cytochrome P450 CYP325A is a major driver of pyrethroid resistance in the major malaria vector Anopheles funestus in Central Africa

Wamba, A. N. R., Ibrahim, S. S., Kusimo, M. O., Muhammad, A., Mugenzi, L. M. J., Irving, H., Wondji, M. J., Hearn, J., Bigoga, J. D. & Wondji, C. S., Nov 2021, In: Insect Biochemistry and Molecular Biology. 138, 103647.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

2020

A 6.5-kb intergenic structural variation enhances P450-mediated resistance to pyrethroids in malaria vectors lowering bed net efficacy

Mugenzi, L. M. J., Menze, B. D., Tchouakui, M., Wondji, M. J., Irving, H., Tchoupo, M., Hearn, J., Weedall, G. D., Riveron, J. M., Cho-Ngwa, F. & Wondji, C. S., Nov 2020, In: Molecular Ecology. 29, 22, p. 4395-4411 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Citations (Scopus)

An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons

Weedall, G. D., Riveron, J. M., Hearn, J., Irving, H., Kamdem, C., Fouet, C., White, B. J. & Wondji, C. S., Jun 2020, In: PLoS Genetics. 16, 6, e1008822.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Citations (Scopus)

A New Genus of Oak Gallwasp, HEOCYNIPS Fang, Nieves-Aldrey, and Melika (Hymenoptera: Cynipidae: Cynipini), from China

Fang, Z., Tang, C. T., Nicholls, J. A., Zhu, Y., Xiong, T., Hearn, J., Sinclair, F., Melika, G., Nieves-Aldrey, J. L., Csóka, G., Mikolajczak, K. M., Stone, G. N. & Fang, S., 1 Oct 2020, In: Proceedings of the Entomological Society of Washington. 122, 4, p. 787-804 18 p.

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

CYP6P9-Driven Signatures of Selective Sweep of Metabolic Resistance to Pyrethroids in the Malaria Vector Anopheles funestus Reveal Contemporary Barriers to Gene Flow

Djuicy, D. D., Hearn, J., Tchouakui, M., Wondji, M. J., Irving, H., Okumu, F. O. & Wondji, C. S., 5 Nov 2020, In: Genes. 11, 11, p. 1-19 19 p., 1314.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Daphnia magna modifies its gene expression extensively in response to caloric restriction revealing a novel effect on haemoglobin isoform preference

Hearn, J., Clark, J., Wilson, P. J. & Little, T. J., Sept 2020, In: Molecular Ecology. 29, 17, p. 3261-3276 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Exploring the Mechanisms of Multiple Insecticide Resistance in a Highly Plasmodium-Infected Malaria Vector Anopheles funestus Sensu Stricto from Sahel of Northern Nigeria

Ibrahim, S. S., Mukhtar, M. M., Irving, H., Riveron, J. M., Fadel, A. N., Tchapga, W., Hearn, J., Muhammad, A., Sarkinfada, F. & Wondji, C. S., 22 Apr 2020, In: Genes. 11, 4, 454.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Scopus)

From Inquilines to Gall Inducers: Genomic Signature of a Life-Style Transition in Synergus Gall Wasps

Gobbo, E., Lartillot, N., Hearn, J., Stone, G. N., Abe, Y., Wheat, C. W., Ide, T. & Ronquist, F., 3 Nov 2020, In: Genome Biology and Evolution. 12, 11, p. 2060-2073 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Scopus)

Lithosaphonecrus edurus Fang, Melika, and Tang, a New Cynipid Inquiline Species (Hymenoptera: Cynipidae: Synergini) from Sichuan, China

Fang, Z., Tang, C. T., Zhu, Y., Xiong, T., Sinclair, F., Hearn, J., Mikolajczak, K. M., Melika, G., Stone, G. N. & Fang, S., 1 Oct 2020, In: Proceedings of the Entomological Society of Washington. 122, 4, p. 805-820 16 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Low-coverage genomic data resolve the population divergence and gene flow history of an Australian rain forest fig wasp

Cooper, L., Bunnefeld, L., Hearn, J., Cook, J. M., Lohse, K. & Stone, G. N., Oct 2020, In: Molecular Ecology. 29, 19, p. 3649-3666 18 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2019

Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus

Mugenzi, L. M. J., Menze, B. D., Tchouakui, M., Wondji, M. J., Irving, H., Tchoupo, M., Hearn, J., Weedall, G. D., Riveron, J. M. & Wondji, C. S., 11 Oct 2019, In: Nature Communications. 10, 1, 4652.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Citations (Scopus)

Clonal Confinement of a Highly Mobile Resistance Element Driven by Combination Therapy in Rhodococcus equi

Álvarez-Narváez, S., Giguère, S., Anastasi, E., Hearn, J., Scortti, M. & Vázquez-Boland, J. A., 15 Oct 2019, In: mBio. 10, 5

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Gall Wasp Transcriptomes Unravel Potential Effectors Involved in Molecular Dialogues With Oak and Rose

Cambier, S., Ginis, O., Moreau, S. J. M., Gayral, P., Hearn, J., Stone, G. N., Giron, D., Huguet, E. & Drezen, J.-M., 24 Jul 2019, In: Frontiers in Physiology. 10, p. 926

Research output: Contribution to journal › Article › peer-review

Open Access

32 Citations (Scopus)

Genome-wide methylation is modified by caloric restriction in Daphnia magna

Hearn, J., Pearson, M., Blaxter, M., Wilson, P. J. & Little, T. J., 8 Mar 2019, In: BMC Genomics. 20, 1, 197.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

Genomic dissection of an extended phenotype: Oak galling by a cynipid gall wasp

Hearn, J., Blaxter, M., Schönrogge, K., Nieves-Aldrey, J.-L., Pujade-Villar, J., Huguet, E., Drezen, J.-M., Shorthouse, J. D. & Stone, G. N., Nov 2019, In: PLoS Genetics. 15, 11, e1008398.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Citations (Scopus)

Listeria monocytogenes isolates from ready to eat plant produce are diverse and have virulence potential

Smith, A., Hearn, J., Taylor, C., Wheelhouse, N., Kaczmarek, M., Moorhouse, E. & Singleton, I., 16 Jun 2019, In: International Journal of Food Microbiology. 299, p. 23-32 10 p.

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

2018

Daphnia magna microRNAs respond to nutritional stress and ageing but are not transgenerational

Hearn, J., Chow, F.W.-N., Barton, H., Tung, M., Wilson, P. J., Blaxter, M., Buck, A. & Little, T. J., Mar 2018, In: Molecular Ecology. 27, 6, p. 1402-1412 11 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Whole-genome data reveal the complex history of a diverse ecological community

Bunnefeld, L., Hearn, J., Stone, G. N. & Lohse, K., 10 Jul 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 28, p. E6507-E6515

Research output: Contribution to journal › Article › peer-review

Open Access

34 Citations (Scopus)

2016

Eight new species of Cycloneuroterus Melika & Tang gallwasps from Taiwan and mainland China (Hymenoptera: Cynipidae: Cynipini)

Tang, C.-T., Sinclair, F., Hearn, J., Yang, M.-M., Stone, G. N., Nicholls, J. A., Schwéger, S. & Melika, G., 11 Mar 2016, In: Zootaxa. 4088, 4, p. 451-88 38 p.

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

2015

New species of cynipid inquilines of the genus Saphonecrus (Hymenoptera: Cynipidae: Synergini) from the Eastern Palaearctic, with a re-appraisal of known species world-wide

Schwéger, S., Melika, G., Tang, C.-T., Yang, M.-M., Stone, G. N., Nicholls, J. A., Sinclair, F., Hearn, J., Bozsó, M. & Pénzes, Z., 8 Dec 2015, In: Zootaxa. 4054, p. 1-84 84 p.

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Using targeted enrichment of nuclear genes to increase phylogenetic resolution in the neotropical rain forest genus Inga (Leguminosae: Mimosoideae)

Nicholls, J. A., Pennington, R. T., Koenen, E. J. M., Hughes, C. E., Hearn, J., Bunnefeld, L., Dexter, K. G., Stone, G. N. & Kidner, C. A., 17 Sept 2015, In: Frontiers in Plant Science. 6, p. 710

Research output: Contribution to journal › Article › peer-review

Open Access

108 Citations (Scopus)

2014

ABC inference of multi-population divergence with admixture from unphased population genomic data

Robinson, J. D., Bunnefeld, L., Hearn, J., Stone, G. N. & Hickerson, M. J., Sept 2014, In: Molecular Ecology. 23, 18, p. 4458-71 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Citations (Scopus)

Likelihood-based inference of population history from low-coverage de novo genome assemblies

Hearn, J., Stone, G. N., Bunnefeld, L., Nicholls, J. A., Barton, N. H. & Lohse, K., Jan 2014, In: Molecular Ecology. 23, 1, p. 198-211 14 p.

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

2013

A new genus of oak gallwasp, Cyclocynips Melika, Tang & Sinclair (Hymenoptera: Cynipidae: Cynipini), with descriptions of two new species from Taiwan

Melika, G., Tang, C. T., Sinclair, F., Yang, M. M., Lohse, K., Hearn, J., Nicholls, J. A. & Stone, G. N., 21 Mar 2013, In: Zootaxa. 3630, 3, p. 534-548 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Citations (Scopus)

2010

Revealing secret liaisons: DNA barcoding changes our understanding of food webs

Kaartinen, R., Stone, G. N., Hearn, J., Lohse, K. & Roslin, T., Oct 2010, In: Ecological Entomology. 35, 5, p. 623-638 16 p.

Research output: Contribution to journal › Article › peer-review

125 Citations (Scopus)

Jack Hearn

Research output

Search results