Research output per year
Research output per year
Personal profile
Research interests
Our understanding of complex tissue interactions at a systems level remains rudimentary, limiting our ability to dissect mechanisms underlying diseases and develop novel therapeutics. Cellular, molecular and mouse models have recently revealed that the skeleton is not merely an endocrine target but also a secretory organ, modulating systemic energy homeostasis. My research therefore focuses on using novel imaging techniques in experimental models and clinical data to determine if bone and cartilage disease alters global metabolism with the purpose of contributing to the development of new pharmacological approaches for managing and treating skeletal, metabolic, and cardiovascular disease.
Teaching
Module Lead: Animal Physiology Systems 2
Contributors: Advanced Physiology of Growth and Development; Academic and Scientific Skills
Supervision
Ben McNeill, BHF PhD: The Role of The Succinate Receptor in Brown Adipose Tissue Function
Projects
The role of matrix-gla protein (MGP) in brown adipose tissue
Education/Academic qualification
Certificate, Data Visualisation for Professionals , University of Edinburgh
Award Date: 1 Jun 2020
PGCert , Postgraduate Certificate Academic Practice
Award Date: 3 Jun 2019
PhD, PHOSPHO1: An example of the interplay between bone mineralisation and energy metabolism, University of Edinburgh
Award Date: 16 Oct 2015
Bachelor, BSc (Hons) Veterinary Science., Royal Veterinary College
Award Date: 1 Jun 2011
External positions
Honorary Fellow, University of Edinburgh
1 Dec 2023 → …
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Collaborations and top research areas from the last five years
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Deletion of Hsd11b1 suppresses caloric restriction-induced bone marrow adiposity in male but not female mice
Lovdel, A., Suchacki, K. J., Roberts, F., Sulston, R. J., Wallace, R. J., Thomas, B. J., Bell, R. M. B., Cervera, I. P., Macpherson, G. J., Morton, N. M., Homer, N. Z. M., Chapman, K. E. & Cawthorn, W. P., 24 Jun 2024, (First published) In: Journal of Endocrinology. 262, 2, e240072.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
The effects of caloric restriction on adipose tissue and metabolic health are sex-and age-dependent.
Suchacki, K. J., Thomas, B. J., Ikushima, Y. M., Chen, K. C., Fyfe, C., Tavares, A. A. S., Sulston, R. J., Lovdel, A., Woodward, H. J., Han, X., Mattiucci, D., Brain, E. J., Alcaide-Corral, C. J., Kobayashi, H., Gray, G. A., Whitfield, P. D., Stimson, R. H., Morton, N. M., Johnstone, A. M. & Cawthorn, W. P., 9 May 2023, In: eLife. 12, e88080.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus) -
The serotonin transporter sustains human brown adipose tissue thermogenesis
Suchacki, K. J., Ramage, L. E., Kwok, T. C., Kelman, A., McNeill, B. T., Rodney, S., Keegan, M., Gray, C., MacNaught, G., Patel, D., Fletcher, A. M., Simpson, J. P., Carter, R. N., Semple, R. K., Homer, N. Z. M., Morton, N. M., van Beek, E. J. R., Wakelin, S. J. & Stimson, R. H., Aug 2023, In: Nature Metabolism. 5, 8, p. 1319-1336 18 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
The diverse and distinct roles of adipose tissue on metabolic health.
Suchacki, K., Dec 2022, 2 p. The Endocrinologist.Research output: Other contribution
Open Access -
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent
Suchacki, K. J., Thomas, B. J., Ikushima, Y. M., Chen, K.-C., Fyfe, C., Tavares, A. A. S., Sulston, R. J., Lovdel, A., Woodward, H. J., Han, X., Mattiucci, D., Brain, E. J., Alcaide-Corral, C. J., Kobayashi, H., Gray, G. A., Whitfield, P. D., Stimson, R. H., Morton, N. M., Johnstone, A. M. & Cawthorn, W. P., 22 Feb 2022, bioRxiv.Research output: Working paper/Preprint › Preprint
Open Access