Projects per year
Personal profile
Personal profile
Professor in Food Safety
Research interests
I am a molecular bacteriologist interested in how some microbes, e.g. foodborne pathogens or hazards such as AMR, are transmitted via environmental sources. I work with stakeholders in public health and the agri-food industry.
My roles are:
- Lead the Safe & Improved Foods challenge-driven research centre
- Lead research into the interactions between human pathogenic bacteria and food products, pre- and post-harvest, to reduce foodborne illness
- Manage Scottish Government strategic research between Scottish research providers
- Supervision of staff, students and visitors; teaching and external examinations
- Committee member for external organisations
Supervision
PhD student (2018-2022) 'Impact of ozone on viability of fooborne and food spoilage pathogens on fresh produce', joint with University of Oxford
PhD student (2017-2021) 'Modelling attachement of bacteria to developing roots', joint with University of Warwick and James Hutton Institute
PhD student (2017-2021) 'Benign enhancement of natural defences: BEYOND', joint with University of Sheffield and James Hutton Institute
Projects
Current:
- 2020-2025: BBSRC BBR “The UK Crop Microbiome Cryobank”. Ryan, Holden (Co-I), Mauchline, Malone (£1.9M, 5 years)
- 2018-2021: Innovate-UK “KTP: microbe management”. Holden, IGS Ltd. (£227K, 3 years)
- 2021: Scottish Government "Scottish One Health AMR Register". Holden (£30K, 4 months)
- 2016-2021: ERC “SENSOILS”. Dupuy, Holden (Co-I), et al. (€1.66M, 5 years)
Previous (selected):
- 2019: NBIC “Listeria biofilms”. Holden, Anacail Ltd (£80K, 1 year)
- 2019-2020: IBiolC “Antimicrobial coatings and matrices”. Love, Holden, et al (£101K, 1 year)
- 2017-2018: Innovate-UK “In-pack ozone”. Holden, Anacail Ltd. (£38K, 1 year)
- 2016-2018: RESAS Innovation fund “Biocontrol”. Holden, partners (FSS, SERL, Kettle) (£132K)
- 2014-2016: FSA “Internalisation”. Holden (£350K)
- 2013-2016: HDC “Plant defence elicitors”. Holden, et al (£300K)
- 2012-2015: The Leverhulme Trust “Plant cell walls”. Holden (£230K)
- 2011-2014: BBSRC “Surface factors colonise plants” Holden (£556K)
- 2011-2011 & 2010-2012: HDC, elicitor grants Holden (£150K)
Education/Academic qualification
PhD, University of Edinburgh
1995 → 1999
External positions
James Hutton Institute
2011 → 2020
Scottish Crop Research Institute, Invergowrie
2007 → 2011
Open University Milton Keynes
2002 → 2007
Centre for Infectious Diseases, School of Biomedical Sciences, Edinburgh Medical School, The University of Edinburgh
2000 → 2007
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Projects
- 1 Active
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Functional Analysis of Shiga Toxin-Producing Escherichia coli Biofilm Components in Plant Leaves
Holden, N. J., Wright, K. M., Marshall, J. & Holmes, A., 12 Mar 2021, (First published) Shiga Toxin-Producing E. coli. Schueller, S. & Bielaszewska, M. (eds.). New York: Springer Science & Business Media, Vol. 2291. p. 163-175 13 p. (Methods in Molecular Biology; vol. 2291).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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MacConkey broth purple provides an efficient MPN estimation method for Shigatoxigenic Escherichia coli
Wright, K., Wright, P. & Holden, NH., Feb 2021, In: Journal of Microbiological Methods. 181, 106132.Research output: Contribution to journal › Article › peer-review
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Microbial cancer therapeutics: A promising approach
Diwan, D., Cheng, L., Usmani, Z., Sharma, M., Holden, N., Willoughby, N., Sangwan, N., Baadhe, R. R., Liu, C. & Gupta, V. K., 9 May 2021, (First published) In: Seminars in Cancer Biology.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
The rise, fall and resurrection of chemical induced resistance agents
Yassin, M., Ton, J., Rolfe, S., Valentine, TA., Cromley, M., Holden, NH. & Newton, A., 17 Mar 2021, (First published) In: Pest Management Science.Research output: Contribution to journal › Review article › peer-review
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A high-throughput genomic screen identifies a role for the plasmid-borne type II secretion system of Escherichia coli O157:H7 (Sakai) in plant-microbe interactions
Holmes, A., Pritchard, L., Hedley, P. E., Morris, J., McAteer, S. P., Gally, D. L. & Holden, NH., Nov 2020, In: Genomics. 112, 6, p. 4242-4253 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
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Microbiology (Journal)
Nicola Holden (Editor)
2021 → …Activity: Publication peer-review and editorial work types › Editorial work
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Keynote on what plant pathology can teach us about human pathogens on plants
Nicola Holden (Speaker)
2018Activity: Talk, evidence or presentation types › Invited talk
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UK Plant Microbiome (External organisation)
Nicola Holden (Member)
2017 → 2021Activity: Membership types › Membership of committee
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Microbiome policy initiative: Microbiology Society (Event)
Nicola Holden (Chair)
2016 → 2017Activity: Membership types › Membership of committee
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EU COST Action (External organisation)
Nicola Holden (Member)
Apr 2016 → Sep 2021Activity: Membership types › Membership of network
Equipment
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Microbiology laboratory (Containment Level 2)
Nicola Holden (Manager)
New North Agri Cost CentreFacility/equipment: Facility