Advances in Nanofabrication Technology for Nutraceuticals: New Insights and Future Trends

Rachitha Puttasiddaiah, Rohitha Lakshminarayana, Nandini Lalithadripura Somashekar, Vijai Kumar Gupta, Baskaran Stephen Inbaraj, Zeba Usmani, Vinay Basavegowda Raghavendra*, Kandi Sridhar, Minaxi Sharma*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)
73 Downloads (Pure)


Bioactive components such as polyphenolics, flavonoids, bioactive peptides, pigments, and essential fatty acids were known to ward off some deadliest diseases. Nutraceuticals are those beneficial compounds that may be food or part of food that has come up with medical or health benefits. Nanoencapsulation and nanofabricated delivery systems are an imminent approach in the field of food sciences. The sustainable fabrication of nutraceuticals and biocompatible active components indisputably enhances the food grade and promotes good health. Nanofabricated delivery systems include carbohydrates-based, lipids (solid and liquid), and proteins-based delivery systems. Solid nano-delivery systems include lipid nanoparticles. Liquid nano-delivery systems include nanoliposomes and nanoemulsions. Physicochemical properties of nanoparticles such as size, charge, hydrophobicity, and targeting molecules affect the absorption, distribution, metabolism, and excretion of nano delivery systems. Advance research in toxicity studies is necessary to ensure the safety of the nanofabricated delivery systems, as the safety of nano delivery systems for use in food applications is unknown. Therefore, improved nanotechnology could play a pivotal role in developing functional foods, a contemporary concept assuring the consumers to provide programmed, high-priced, and high-quality research toward nanofabricated delivery systems.

Original languageEnglish
Article number478
Issue number9
Early online date16 Sept 2022
Publication statusFirst published - 16 Sept 2022


  • liposomes
  • nano-emulsions
  • nano-formulation
  • nanofabricated delivery system
  • nutraceuticals
  • prebiotics


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