TY - JOUR
T1 - Advances in Nanofabrication Technology for Nutraceuticals
T2 - New Insights and Future Trends
AU - Puttasiddaiah, Rachitha
AU - Lakshminarayana, Rohitha
AU - Somashekar, Nandini Lalithadripura
AU - Gupta, Vijai Kumar
AU - Inbaraj, Baskaran Stephen
AU - Usmani, Zeba
AU - Raghavendra, Vinay Basavegowda
AU - Sridhar, Kandi
AU - Sharma, Minaxi
PY - 2022/9/16
Y1 - 2022/9/16
N2 - Bioactive components such as polyphenolics, flavonoids, bioactive peptides, pigments, and essential fatty acids were known to ward off some deadliest diseases. Nutraceuticals are those beneficial compounds that may be food or part of food that has come up with medical or health benefits. Nanoencapsulation and nanofabricated delivery systems are an imminent approach in the field of food sciences. The sustainable fabrication of nutraceuticals and biocompatible active components indisputably enhances the food grade and promotes good health. Nanofabricated delivery systems include carbohydrates-based, lipids (solid and liquid), and proteins-based delivery systems. Solid nano-delivery systems include lipid nanoparticles. Liquid nano-delivery systems include nanoliposomes and nanoemulsions. Physicochemical properties of nanoparticles such as size, charge, hydrophobicity, and targeting molecules affect the absorption, distribution, metabolism, and excretion of nano delivery systems. Advance research in toxicity studies is necessary to ensure the safety of the nanofabricated delivery systems, as the safety of nano delivery systems for use in food applications is unknown. Therefore, improved nanotechnology could play a pivotal role in developing functional foods, a contemporary concept assuring the consumers to provide programmed, high-priced, and high-quality research toward nanofabricated delivery systems.
AB - Bioactive components such as polyphenolics, flavonoids, bioactive peptides, pigments, and essential fatty acids were known to ward off some deadliest diseases. Nutraceuticals are those beneficial compounds that may be food or part of food that has come up with medical or health benefits. Nanoencapsulation and nanofabricated delivery systems are an imminent approach in the field of food sciences. The sustainable fabrication of nutraceuticals and biocompatible active components indisputably enhances the food grade and promotes good health. Nanofabricated delivery systems include carbohydrates-based, lipids (solid and liquid), and proteins-based delivery systems. Solid nano-delivery systems include lipid nanoparticles. Liquid nano-delivery systems include nanoliposomes and nanoemulsions. Physicochemical properties of nanoparticles such as size, charge, hydrophobicity, and targeting molecules affect the absorption, distribution, metabolism, and excretion of nano delivery systems. Advance research in toxicity studies is necessary to ensure the safety of the nanofabricated delivery systems, as the safety of nano delivery systems for use in food applications is unknown. Therefore, improved nanotechnology could play a pivotal role in developing functional foods, a contemporary concept assuring the consumers to provide programmed, high-priced, and high-quality research toward nanofabricated delivery systems.
KW - liposomes
KW - nano-emulsions
KW - nano-formulation
KW - nanofabricated delivery system
KW - nutraceuticals
KW - prebiotics
UR - http://www.scopus.com/inward/record.url?scp=85138665146&partnerID=8YFLogxK
U2 - 10.3390/bioengineering9090478
DO - 10.3390/bioengineering9090478
M3 - Review article
C2 - 36135026
AN - SCOPUS:85138665146
SN - 2306-5354
VL - 9
JO - Bioengineering
JF - Bioengineering
IS - 9
M1 - 478
ER -