Age-dependent prevalence of anti-Brucella antibodies in hooded seals Cystophora cristata

IH Nymo, M Tryland, AK Frie, T Haug, G Foster, R Rodven, J Godfroid

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Investigations of hooded seals Cystophora cristata have revealed high prevalences of Brucella-positive seals in the reduced Northeast Atlantic stock, compared to the increasing Northwest Atlantic stock. This study evaluated the relation between Brucella-serostatus in seals in the Northeast Atlantic stock and age, sex, body condition and reproduction. Bacteriology documented which animals and organs were B. pinnipedialis positive. No relationship was observed between Brucella-serostatus and body condition or reproductive traits. Pups (<1 mo old) had a substantially lower probability of being seropositive (4/159, 2.5%) than yearlings (6/17, 35.3%), suggesting that exposure may occur post-weaning, during the first year of life. For seals >1 yr old, the mean probability of being seropositive decreased with age, with no seropositives older than 5 yr, indicating loss of antibody titre with either chronicity or clearance of infection. The latter explanation seems to be most likely as B. pinnipedialis has never been isolated from a hooded seal >18 mo old, which is consistent with findings in this study; B. pinnipedialis was isolated from the retropharyngeal lymph node in 1 seropositive yearling (1/21, 5%). We hypothesize that this serological and bacteriological pattern is due to environmental exposure to B. pinnipedialis early in life, with a subsequent clearance of infection. This raises the question of a reservoir of B. pinnipedialis in the hooded seal food web.
Original languageEnglish
Pages (from-to)187 - 196
Number of pages10
JournalDiseases of Aquatic Organisms
Volume106
Issue number3
Early online dateNov 2013
DOIs
Publication statusPrint publication - 2013

Fingerprint

Brucella
Anti-Idiotypic Antibodies
Animal Structures
Bacteriology
Food Chain
Environmental Exposure
Infection
Weaning
Reproduction
Antibodies

Keywords

  • Atlantic hooded seal stock
  • Bacteriology
  • Brucellosis
  • Food web
  • Infection clearance
  • Pinniped
  • Pups
  • Serostatus

Cite this

Nymo, IH ; Tryland, M ; Frie, AK ; Haug, T ; Foster, G ; Rodven, R ; Godfroid, J. / Age-dependent prevalence of anti-Brucella antibodies in hooded seals Cystophora cristata. In: Diseases of Aquatic Organisms. 2013 ; Vol. 106, No. 3. pp. 187 - 196.
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Nymo, IH, Tryland, M, Frie, AK, Haug, T, Foster, G, Rodven, R & Godfroid, J 2013, 'Age-dependent prevalence of anti-Brucella antibodies in hooded seals Cystophora cristata', Diseases of Aquatic Organisms, vol. 106, no. 3, pp. 187 - 196. https://doi.org/10.3354/dao02659

Age-dependent prevalence of anti-Brucella antibodies in hooded seals Cystophora cristata. / Nymo, IH; Tryland, M; Frie, AK; Haug, T; Foster, G; Rodven, R; Godfroid, J.

In: Diseases of Aquatic Organisms, Vol. 106, No. 3, 2013, p. 187 - 196.

Research output: Contribution to journalArticle

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T1 - Age-dependent prevalence of anti-Brucella antibodies in hooded seals Cystophora cristata

AU - Nymo, IH

AU - Tryland, M

AU - Frie, AK

AU - Haug, T

AU - Foster, G

AU - Rodven, R

AU - Godfroid, J

PY - 2013

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AB - Investigations of hooded seals Cystophora cristata have revealed high prevalences of Brucella-positive seals in the reduced Northeast Atlantic stock, compared to the increasing Northwest Atlantic stock. This study evaluated the relation between Brucella-serostatus in seals in the Northeast Atlantic stock and age, sex, body condition and reproduction. Bacteriology documented which animals and organs were B. pinnipedialis positive. No relationship was observed between Brucella-serostatus and body condition or reproductive traits. Pups (<1 mo old) had a substantially lower probability of being seropositive (4/159, 2.5%) than yearlings (6/17, 35.3%), suggesting that exposure may occur post-weaning, during the first year of life. For seals >1 yr old, the mean probability of being seropositive decreased with age, with no seropositives older than 5 yr, indicating loss of antibody titre with either chronicity or clearance of infection. The latter explanation seems to be most likely as B. pinnipedialis has never been isolated from a hooded seal >18 mo old, which is consistent with findings in this study; B. pinnipedialis was isolated from the retropharyngeal lymph node in 1 seropositive yearling (1/21, 5%). We hypothesize that this serological and bacteriological pattern is due to environmental exposure to B. pinnipedialis early in life, with a subsequent clearance of infection. This raises the question of a reservoir of B. pinnipedialis in the hooded seal food web.

KW - Atlantic hooded seal stock

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KW - Infection clearance

KW - Pinniped

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