Antifungal agents in agriculture: Friends and foes of public health

Veronica Soares Brauer, Caroline Patini Rezende, Andre Moreira Pessoni, Renato Graciano De Paula, Kanchugarakoppal S. Rangappa, Siddaiah Chandra Nayaka, Vijai Kumar Gupta*, Fausto Almeida

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

173 Citations (Scopus)


Fungal diseases have been underestimated worldwide but constitute a substantial threat to several plant and animal species as well as to public health. The increase in the global population has entailed an increase in the demand for agriculture in recent decades. Accordingly, there has been worldwide pressure to find means to improve the quality and productivity of agricultural crops. Antifungal agents have been widely used as an alternative for managing fungal diseases affecting several crops. However, the unregulated use of antifungals can jeopardize public health. Application of fungicides in agriculture should be under strict regulation to ensure the toxicological safety of commercialized foods. This review discusses the use of antifungals in agriculture worldwide, the need to develop new antifungals, and improvement of regulations regarding antifungal use.

Original languageEnglish
Article number521
Issue number10
Early online date23 Sept 2019
Publication statusPrint publication - Oct 2019
Externally publishedYes


  • Agriculture
  • Antifungal agents
  • Chemoinformatics
  • Fungicides


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