Bacterial Adherence to Plant and Animal Surfaces Via Adhesin-Lipid Interactions

Claire Rossi, Helene Cazzola, NH Holden, Yannick Rossez*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The plasma membrane acts as one of the first lines of defense by establishing a physical barrier against microbes. Nevertheless, bacteria have developed a range of strategies to invade the host tissues efficiently. In this chapter, we focus on this understudied area and describe how bacteria target or redirect host membrane lipids. Domains enriched in sterols and sphingolipids, denominated membrane rafts, in particular, have been reported to be exploited by numerous bacterial pathogens. We will first describe the different strategies employed by bacteria to specifically target the PM via membrane rafts and non-raft counterpart domains; and secondly, we illustrate how development of biomimetic membranes has identified bacterial mechanisms of interaction.
Original languageEnglish
Title of host publicationHealth Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids
EditorsHoward Goldfine
Place of PublicationSwitzerland
ISBN (Electronic)978-3-319-72473-7
Publication statusPrint publication - 27 Sept 2019
Externally publishedYes

Publication series

NameHandbook of Hydrocarbon and Lipid Microbiology


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