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Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity
R.A. Morgan
, K.R. Beck
, M. Nixon
, N.Z.M. Homer
, A.A. Crawford
, D. Melchers
, R. Houtman
, O.C. Meijer
, A. Stomby
, A.J. Anderson
, R. Upreti
, R.H. Stimson
, T. Olsson
, T. Michoel
, A. Cohain
, A. Ruusalepp
, E.E. Schadt
, J.L.M. Björkegren
, R. Andrew
, C.J. Kenyon
P.W.F. Hadoke, A. Odermatt, J.A. Keen, B.R. Walker
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Research output
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Contribution to journal
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Article
›
peer-review
24
Citations (Scopus)
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Dive into the research topics of 'Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity'. Together they form a unique fingerprint.
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Biochemistry, Genetics and Molecular Biology
Agonist
14%
Cortisol
28%
Drug Metabolism
14%
Eicosanoid Receptor
100%
Glucocorticoid
100%
Glucocorticoid Receptor
57%
Metabolic Pathway
28%
Mouse
28%
Oxidoreductase
100%
Reductase
100%
Pharmacology, Toxicology and Pharmaceutical Science
Carbonyl Reductase
100%
Diet Induced Obesity
14%
Endogenous Agonist
14%
Glucocorticoid
100%
Glucocorticoid Receptor
57%
Glucose Intolerance
14%
Hydrallostane
28%
Hydrocortisone
28%
Mouse
28%
Receptor
100%
Reduced Nicotinamide Adenine Dinucleotide Phosphate
14%