Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury

Pierpaolo Di Giminiani*, DA Sandercock, Mette Herskin, Emma Malcolm, M Leach, SA Edwards

*Corresponding author for this work

Research output: Contribution to conferenceAbstractResearchpeer-review

Abstract

To date, studies on pain arising from tail docking and tail biting in pigs have mainly focussed on non-evoked behaviours. The development of neuromas and possible abnormal neural activity prompted us to target changes in nociceptive thresholds. We investigated the feasibility of pressure algometry applied to the tail of unrestrained pigs to quantify sensitisation following simulated tail biting and neonatal tail docking. Mechanical nociceptive thresholds (MNT) were determined in 3 tail regions (1: proximal; 2: intermediate; 3: distal) with a Pressure Application Measurement device (PAM). MNT were measured in pigs of 9 (n=41) and 17 weeks of age (n=67) at baseline and one week following resection. To evaluate the effect of time since injury, a subsample of pigs was tested at 8 (n=24), and 16 (n=38) weeks post-resection. Severity of injury was assessed using 3 treatments: ‘Intact’ (sham-resection); ‘short tail’ (2/3 of tail removed); ‘long tail’ (1/3 of tail removed). MNT were also recorded in 17 week-old pigs tail-docked at 3 days of age (n=23) according to the 3 treatments. The PAM induced clear withdrawal responses (response rate 95.2 %). Pre-resection MNT were higher in region 1 vs. 2 and 3 (P<0.05). Higher pre-resection MNT were recorded in 17 vs. 9 week-old pigs (P<0.05). Intra-individual and intra-site variability in MNT was 30% with a fair-to-good level of consistency (Intra-class Correlation Coefficient). One week post-resection, MNT were lower in resected (P<0.05), but not intact tails. Similarly, MNT were lower than intact values at 16 weeks following resections at 9 weeks of age (P<0.05). For resections at 17 weeks of age, MNT were lower in long vs. intact at 8 weeks after resection (P<0.05), but no significant difference was observed at 16 weeks following surgery (Two-way Repeated Measures ANOVA for all comparisons). No difference in MNT was recorded across treatments 17 weeks after neonatal docking. The PAM was an effective method for the assessment of MNT in intact and resected tails. Tail injury resulted in acute sensitisation. Long lasting effects were seen up to 16 weeks post-resection performed at 9 weeks, but were not apparent 16 weeks after neonatal docking or resections performed at 17 weeks. The current results provide novel information on the welfare compromise due to tail damage early or later in the life of pigs and inform assessment of the trade-off between tail docking and the risk of tail biting.
Original languageEnglish
Number of pages1
Publication statusPrint publication - 12 Jul 2016
Event50th International Society for Applied Ethology (ISAE) Congress 2016 - Edinburgh, United Kingdom
Duration: 12 Jul 201616 Jul 2016
https://www.applied-ethology.org/res/2016%20ISAE%20Edinburgh.pdf

Conference

Conference50th International Society for Applied Ethology (ISAE) Congress 2016
CountryUnited Kingdom
CityEdinburgh
Period12/07/1616/07/16
Internet address

Fingerprint

resection
tail
swine
tail docking
application parameters
placebos
pain
surgery
analysis of variance

Keywords

  • Mechanical nociceptive thresholds
  • Pig welfare
  • Pig production
  • Painful procedures
  • Mechanical hyperalgesia
  • Mechanical allodynia
  • Tail amputation
  • Tail biting

Cite this

Di Giminiani, P., Sandercock, DA., Herskin, M., Malcolm, E., Leach, M., & Edwards, SA. (2016). Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury. Abstract from 50th International Society for Applied Ethology (ISAE) Congress 2016, Edinburgh, United Kingdom.
Di Giminiani, Pierpaolo ; Sandercock, DA ; Herskin, Mette ; Malcolm, Emma ; Leach, M ; Edwards, SA. / Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury. Abstract from 50th International Society for Applied Ethology (ISAE) Congress 2016, Edinburgh, United Kingdom.1 p.
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Di Giminiani, P, Sandercock, DA, Herskin, M, Malcolm, E, Leach, M & Edwards, SA 2016, 'Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury' 50th International Society for Applied Ethology (ISAE) Congress 2016, Edinburgh, United Kingdom, 12/07/16 - 16/07/16, .

Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury. / Di Giminiani, Pierpaolo; Sandercock, DA; Herskin, Mette; Malcolm, Emma; Leach, M; Edwards, SA.

2016. Abstract from 50th International Society for Applied Ethology (ISAE) Congress 2016, Edinburgh, United Kingdom.

Research output: Contribution to conferenceAbstractResearchpeer-review

TY - CONF

T1 - Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury

AU - Di Giminiani, Pierpaolo

AU - Sandercock, DA

AU - Herskin, Mette

AU - Malcolm, Emma

AU - Leach, M

AU - Edwards, SA

PY - 2016/7/12

Y1 - 2016/7/12

N2 - To date, studies on pain arising from tail docking and tail biting in pigs have mainly focussed on non-evoked behaviours. The development of neuromas and possible abnormal neural activity prompted us to target changes in nociceptive thresholds. We investigated the feasibility of pressure algometry applied to the tail of unrestrained pigs to quantify sensitisation following simulated tail biting and neonatal tail docking. Mechanical nociceptive thresholds (MNT) were determined in 3 tail regions (1: proximal; 2: intermediate; 3: distal) with a Pressure Application Measurement device (PAM). MNT were measured in pigs of 9 (n=41) and 17 weeks of age (n=67) at baseline and one week following resection. To evaluate the effect of time since injury, a subsample of pigs was tested at 8 (n=24), and 16 (n=38) weeks post-resection. Severity of injury was assessed using 3 treatments: ‘Intact’ (sham-resection); ‘short tail’ (2/3 of tail removed); ‘long tail’ (1/3 of tail removed). MNT were also recorded in 17 week-old pigs tail-docked at 3 days of age (n=23) according to the 3 treatments. The PAM induced clear withdrawal responses (response rate 95.2 %). Pre-resection MNT were higher in region 1 vs. 2 and 3 (P<0.05). Higher pre-resection MNT were recorded in 17 vs. 9 week-old pigs (P<0.05). Intra-individual and intra-site variability in MNT was 30% with a fair-to-good level of consistency (Intra-class Correlation Coefficient). One week post-resection, MNT were lower in resected (P<0.05), but not intact tails. Similarly, MNT were lower than intact values at 16 weeks following resections at 9 weeks of age (P<0.05). For resections at 17 weeks of age, MNT were lower in long vs. intact at 8 weeks after resection (P<0.05), but no significant difference was observed at 16 weeks following surgery (Two-way Repeated Measures ANOVA for all comparisons). No difference in MNT was recorded across treatments 17 weeks after neonatal docking. The PAM was an effective method for the assessment of MNT in intact and resected tails. Tail injury resulted in acute sensitisation. Long lasting effects were seen up to 16 weeks post-resection performed at 9 weeks, but were not apparent 16 weeks after neonatal docking or resections performed at 17 weeks. The current results provide novel information on the welfare compromise due to tail damage early or later in the life of pigs and inform assessment of the trade-off between tail docking and the risk of tail biting.

AB - To date, studies on pain arising from tail docking and tail biting in pigs have mainly focussed on non-evoked behaviours. The development of neuromas and possible abnormal neural activity prompted us to target changes in nociceptive thresholds. We investigated the feasibility of pressure algometry applied to the tail of unrestrained pigs to quantify sensitisation following simulated tail biting and neonatal tail docking. Mechanical nociceptive thresholds (MNT) were determined in 3 tail regions (1: proximal; 2: intermediate; 3: distal) with a Pressure Application Measurement device (PAM). MNT were measured in pigs of 9 (n=41) and 17 weeks of age (n=67) at baseline and one week following resection. To evaluate the effect of time since injury, a subsample of pigs was tested at 8 (n=24), and 16 (n=38) weeks post-resection. Severity of injury was assessed using 3 treatments: ‘Intact’ (sham-resection); ‘short tail’ (2/3 of tail removed); ‘long tail’ (1/3 of tail removed). MNT were also recorded in 17 week-old pigs tail-docked at 3 days of age (n=23) according to the 3 treatments. The PAM induced clear withdrawal responses (response rate 95.2 %). Pre-resection MNT were higher in region 1 vs. 2 and 3 (P<0.05). Higher pre-resection MNT were recorded in 17 vs. 9 week-old pigs (P<0.05). Intra-individual and intra-site variability in MNT was 30% with a fair-to-good level of consistency (Intra-class Correlation Coefficient). One week post-resection, MNT were lower in resected (P<0.05), but not intact tails. Similarly, MNT were lower than intact values at 16 weeks following resections at 9 weeks of age (P<0.05). For resections at 17 weeks of age, MNT were lower in long vs. intact at 8 weeks after resection (P<0.05), but no significant difference was observed at 16 weeks following surgery (Two-way Repeated Measures ANOVA for all comparisons). No difference in MNT was recorded across treatments 17 weeks after neonatal docking. The PAM was an effective method for the assessment of MNT in intact and resected tails. Tail injury resulted in acute sensitisation. Long lasting effects were seen up to 16 weeks post-resection performed at 9 weeks, but were not apparent 16 weeks after neonatal docking or resections performed at 17 weeks. The current results provide novel information on the welfare compromise due to tail damage early or later in the life of pigs and inform assessment of the trade-off between tail docking and the risk of tail biting.

KW - Mechanical nociceptive thresholds

KW - Pig welfare

KW - Pig production

KW - Painful procedures

KW - Mechanical hyperalgesia

KW - Mechanical allodynia

KW - Tail amputation

KW - Tail biting

M3 - Abstract

ER -

Di Giminiani P, Sandercock DA, Herskin M, Malcolm E, Leach M, Edwards SA. Characterisation of short and long-term changes in mechanical nociceptive thresholds in pigs following tail injury. 2016. Abstract from 50th International Society for Applied Ethology (ISAE) Congress 2016, Edinburgh, United Kingdom.