Detection and effects of harmful algal toxins in Scottish harbour seals and potential links to population decline

S-K Jensen, J-P Lacaze, G Hermann, J Kershaw, A Brownlow, A Turner

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Over the past 15 years or so, several Scottish harbour seal (Phoca vitulina) populations have declined in abundance and several factors have been considered as possible causes, including toxins from harmful algae. Here we explore whether a link could be established between two groups of toxins, domoic acid (DA) and saxitoxins (STXs), and the decline in the harbour seal populations in Scotland. We document the first evidence that harbour seals are exposed to both DA and STXs from consuming contaminated fish. Both groups of toxins were found in urine and faeces sampled from live captured (n ¼ 162) and stranded animals (n ¼ 23) and in faecal samples collected from seal haul-out sites (n ¼ 214) between 2008 and 2013. The proportion of positive samples and the toxins levels measured in the excreta were significantly higher in areas where harbour seal abundance is in decline. There is also evidence that DA has immunomodulatory effects in harbour seals, including lymphocytopenia and monocytosis. Scottish harbour seals are exposed to DA and STXs through contaminated prey at potentially lethal levels and with this evidence we suggest that exposure to these toxins are likely to be important factors driving the harbour seal decline in some regions of Scotland. © 2015 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)1 - 14
Number of pages14
JournalToxicon
Volume97
DOIs
Publication statusFirst published - 7 Feb 2015

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phycotoxins
Phoca vitulina
saxitoxins
domoic acid
toxins
seals
Scotland
excreta
urine
feces
sampling

Keywords

  • Domoic acid (DA)
  • HABs
  • Marine mammal
  • Paralytic Shellfish Poisoning (PSP) toxins
  • Phoca vitulina
  • Scotland

Cite this

Jensen, S-K ; Lacaze, J-P ; Hermann, G ; Kershaw, J ; Brownlow, A ; Turner, A. / Detection and effects of harmful algal toxins in Scottish harbour seals and potential links to population decline. In: Toxicon. 2015 ; Vol. 97. pp. 1 - 14.
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abstract = "Over the past 15 years or so, several Scottish harbour seal (Phoca vitulina) populations have declined in abundance and several factors have been considered as possible causes, including toxins from harmful algae. Here we explore whether a link could be established between two groups of toxins, domoic acid (DA) and saxitoxins (STXs), and the decline in the harbour seal populations in Scotland. We document the first evidence that harbour seals are exposed to both DA and STXs from consuming contaminated fish. Both groups of toxins were found in urine and faeces sampled from live captured (n ¼ 162) and stranded animals (n ¼ 23) and in faecal samples collected from seal haul-out sites (n ¼ 214) between 2008 and 2013. The proportion of positive samples and the toxins levels measured in the excreta were significantly higher in areas where harbour seal abundance is in decline. There is also evidence that DA has immunomodulatory effects in harbour seals, including lymphocytopenia and monocytosis. Scottish harbour seals are exposed to DA and STXs through contaminated prey at potentially lethal levels and with this evidence we suggest that exposure to these toxins are likely to be important factors driving the harbour seal decline in some regions of Scotland. {\circledC} 2015 Elsevier Ltd. All rights reserved.",
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Detection and effects of harmful algal toxins in Scottish harbour seals and potential links to population decline. / Jensen, S-K; Lacaze, J-P; Hermann, G; Kershaw, J; Brownlow, A; Turner, A.

In: Toxicon, Vol. 97, 07.02.2015, p. 1 - 14.

Research output: Contribution to journalArticle

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AU - Turner, A

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AB - Over the past 15 years or so, several Scottish harbour seal (Phoca vitulina) populations have declined in abundance and several factors have been considered as possible causes, including toxins from harmful algae. Here we explore whether a link could be established between two groups of toxins, domoic acid (DA) and saxitoxins (STXs), and the decline in the harbour seal populations in Scotland. We document the first evidence that harbour seals are exposed to both DA and STXs from consuming contaminated fish. Both groups of toxins were found in urine and faeces sampled from live captured (n ¼ 162) and stranded animals (n ¼ 23) and in faecal samples collected from seal haul-out sites (n ¼ 214) between 2008 and 2013. The proportion of positive samples and the toxins levels measured in the excreta were significantly higher in areas where harbour seal abundance is in decline. There is also evidence that DA has immunomodulatory effects in harbour seals, including lymphocytopenia and monocytosis. Scottish harbour seals are exposed to DA and STXs through contaminated prey at potentially lethal levels and with this evidence we suggest that exposure to these toxins are likely to be important factors driving the harbour seal decline in some regions of Scotland. © 2015 Elsevier Ltd. All rights reserved.

KW - Domoic acid (DA)

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