Extending the durability of cultivar resistance by limiting epidemic growth rates

K Carolan, J Helps, F van den Berg, RA Bain, N Paveley, F van den Bosch

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cultivar resistance is an essential part of disease control programmes in many agricultural systems. The use of resistant cultivars applies a selection pressure on pathogen populations for the evolution of virulence, resulting in loss of disease control. Various techniques for the deployment of host resistance genes have been proposed to reduce the selection for virulence, but these are often difficult to apply in practice. We present a general technique to maintain the effectiveness of cultivar resistance. Derived from classical population genetics theory; any factor that reduces the population growth rates of both the virulent and avirulent strains will reduce selection. We model the specific example of fungicide application to reduce the growth rates of virulent and avirulent strains of a pathogen, demonstrating that appropriate use of fungicides reduces selection for virulence, prolonging cultivar resistance. This specific example of chemical control illustrates a general principle for the development of techniques to manage the evolution of virulence by slowing epidemic growth rates.
Original languageEnglish
JournalProceedings of the Royal Society B: Biological Sciences
Volume284
Issue number1863
Early online date20 Sep 2017
DOIs
Publication statusFirst published - 20 Sep 2017

Fingerprint

durability
virulence
avirulent strains
cultivars
disease control programs
pathogens
chemical control
pesticide application
fungicides
population genetics
population growth
disease control
methodology
genes
virulent strains

Bibliographical note

1025159

Keywords

  • Evolution
  • Fungicide
  • Integrated disease control
  • Selection
  • Virulence
  • Virulence management

Cite this

Carolan, K ; Helps, J ; van den Berg, F ; Bain, RA ; Paveley, N ; van den Bosch, F. / Extending the durability of cultivar resistance by limiting epidemic growth rates. In: Proceedings of the Royal Society B: Biological Sciences. 2017 ; Vol. 284, No. 1863.
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Extending the durability of cultivar resistance by limiting epidemic growth rates. / Carolan, K; Helps, J; van den Berg, F; Bain, RA; Paveley, N; van den Bosch, F.

In: Proceedings of the Royal Society B: Biological Sciences, Vol. 284, No. 1863, 20.09.2017.

Research output: Contribution to journalArticle

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T1 - Extending the durability of cultivar resistance by limiting epidemic growth rates

AU - Carolan, K

AU - Helps, J

AU - van den Berg, F

AU - Bain, RA

AU - Paveley, N

AU - van den Bosch, F

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