Functional SNP panel for parentage assessment and assignment in worldwide goat breeds

Andrea Talenti, Isabelle Palhière, Flavie Tortereau, Giulio Pagnacco, Alessandra Stella, Ezequiel L Nicolazzi, Paola Crepaldi, Gwenola Tosser-Klopp, AdaptMap consortium

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND: International standard panels of single nucleotide polymorphisms (SNPs) have replaced microsatellites in several species for parentage assessment and assignment (PA) purposes. However, such a resource is still lacking in goats. The application of a cheap tool for PA would help the management of goat populations by improving the reliability of pedigree registration and, consequently, allow a better implementation of breeding schemes or conservation programs.

RESULTS: Using data from the current GoatSNP50 chip, starting from a worldwide dataset of more than 4000 animals belonging to more than 140 breeds and populations from the AdaptMap initiative, we selected a panel of 195 SNPs. The assignment rate of this panel was up to 100% on an additional dataset that included 2000 Alpine and Saanen animals and highly related candidate sires.

CONCLUSIONS: In this study, we defined a highly informative SNP panel, which will be publicly available to worldwide breeders and laboratories. Its development on such a large number of breeds and populations, together with validation on a second set of cosmopolitan breeds, makes it a promising and important genomic tool for the goat species.

Original languageEnglish
Pages (from-to)55
JournalGenetics Selection Evolution
Volume50
Issue number1
DOIs
Publication statusPrint publication - 19 Nov 2018
Externally publishedYes

Keywords

  • Animals
  • Breeding/methods
  • Female
  • Gene Frequency
  • Goats/genetics
  • Linkage Disequilibrium
  • Male
  • Polymorphism, Single Nucleotide
  • Sex Determination Processes

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    Cite this

    Talenti, A., Palhière, I., Tortereau, F., Pagnacco, G., Stella, A., Nicolazzi, E. L., Crepaldi, P., Tosser-Klopp, G., & AdaptMap consortium (2018). Functional SNP panel for parentage assessment and assignment in worldwide goat breeds. Genetics Selection Evolution, 50(1), 55. https://doi.org/10.1186/s12711-018-0423-9