Impact of temperature, feeding preference and vaccination on Schmallenberg virus transmission in Scotland

PR Bessell, HK Auty, KR Searle, IG Handel, BV Purse, BMdeC Bronsvoort

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

First identified in 2011, Schmallenberg virus (SBV) is principally transmitted by Culicoides midges and affects ruminants. Clinical presentation is typified by foetal abnormalities, but despite very high infection rates, relatively few animals present with clinical signs. In this paper we further develop a previously published stochastic mathematical model of SBV spread to investigate the optimal deployment of a vaccine for SBV in Scotland, a country that has experienced only sporadic and isolated cases of SBV.Weconsider the use of the vaccine under different temperatures and explore the effects of a vector preference for feeding on cattle. We demonstrate that vaccine impact is optimised by targeting it at the high risk areas in the south of Scotland, or vaccinating only cattle. At higher than average temperatures, and hence increased transmission potential, the relative impact of vaccination is considerably enhanced. Vaccine impact is also enhanced if vectors feed preferentially on cattle. These findings are of considerable importance when planning control strategies for SBV and also have important implications for management of other arboviruses such as Bluetongue virus. Environmental determinants and feeding preferences should be researched further to inform development of effective control strategies.
Original languageEnglish
JournalScientific Reports
Volume4
Issue number5746
DOIs
Publication statusFirst published - 2014

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Scotland
Vaccination
Viruses
Temperature
Vaccines
Ceratopogonidae
Arboviruses
Ruminants
Theoretical Models

Bibliographical note

1023410

Keywords

  • Computational models
  • Ecological epidemiology
  • Entomology

Cite this

Bessell, PR ; Auty, HK ; Searle, KR ; Handel, IG ; Purse, BV ; Bronsvoort, BMdeC. / Impact of temperature, feeding preference and vaccination on Schmallenberg virus transmission in Scotland. In: Scientific Reports. 2014 ; Vol. 4, No. 5746.
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Bessell, PR, Auty, HK, Searle, KR, Handel, IG, Purse, BV & Bronsvoort, BM 2014, 'Impact of temperature, feeding preference and vaccination on Schmallenberg virus transmission in Scotland', Scientific Reports, vol. 4, no. 5746. https://doi.org/10.1038/srep05746

Impact of temperature, feeding preference and vaccination on Schmallenberg virus transmission in Scotland. / Bessell, PR; Auty, HK; Searle, KR; Handel, IG; Purse, BV; Bronsvoort, BMdeC.

In: Scientific Reports, Vol. 4, No. 5746, 2014.

Research output: Contribution to journalArticle

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T1 - Impact of temperature, feeding preference and vaccination on Schmallenberg virus transmission in Scotland

AU - Bessell, PR

AU - Auty, HK

AU - Searle, KR

AU - Handel, IG

AU - Purse, BV

AU - Bronsvoort, BMdeC

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