Insights into the synthesis and mechanism of green synthesized antimicrobial nanoparticles, answer to the multidrug resistance

D. Sharma, P. Shandilya, N. K. Saini, P. Singh, V. K. Thakur, R. V. Saini, D. Mittal, G. Chandan, V. Saini, A. K. Saini*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Emergence of the multidrug resistant human pathogenic strains is posing a serious health challenge. Resistant strains carry mutations which help them to resist conventional drugs. Therefore, it is required to produce more effective agents that are able to degrade the resistant pathogenic bacterial strains. The antimicrobial properties of nanoparticles (NPs) by eco-friendly green synthetic methods have pulled attention everywhere owing to their exceptional properties and small particle size of 100 nm. NPs are considered to belong to a group of antimicrobial agents which have ability to go inside microbial cells and kill them. In this comprehensive review, we are discussing the green synthetic methods used for the synthesis of NPs targeting the microbes. Additionally, several characterization techniques of antimicrobial NPs are also discussed. Subsequently, various methods used for the analysis of antimicrobial activities and their mechanisms are also examined.

Original languageEnglish
Article number100391
JournalMaterials Today Chemistry
Volume19
Early online date10 Dec 2020
DOIs
Publication statusPrint publication - Mar 2021

Keywords

  • Antimicrobial activities
  • Antimicrobial mechanisms
  • Bacterial species
  • DNA damage
  • Nanoparticles
  • Reactive oxygen species

Fingerprint Dive into the research topics of 'Insights into the synthesis and mechanism of green synthesized antimicrobial nanoparticles, answer to the multidrug resistance'. Together they form a unique fingerprint.

Cite this