Twenty-one of the world's prolific sheep breeds and strains were tested for the presence of the FecB mutation of BMPR1B and the FecXI mutation of BMP15. The breeds studied were Romanov (2 strains), Finn (2 strains), East Friesian, Teeswater, Blueface Leicester, Hu, Han, D'Man, Chios, Mountain Sheep (three breeds), German Whiteheaded Mutton, Lleyn, Loa, Galician, Barbados Blackbelly (pure and crossbred) and St. Croix. The FecB mutation was found in two breeds, Hu and Han from China, but not in any of the other breeds. The 12 Hu sheep sampled were all homozygous carriers of FecB (FecBB/FecB B) whereas the sample of 12 Han sheep included all three genotypes (FecBB/FecBB, FecBB/FecB+, FecB +/FecB+) at frequencies of 0.33, 0.58 and 0.08, respectively. There was no evidence of FecXI in any of the breeds sampled.
- Major gene