Juvenile harbor porpoises in the UK are exposed to a more neurotoxic mixture of polychlorinated biphenyls than adults

Rosie S. Williams*, David J. Curnick, Jonathan L. Barber, Andrew Brownlow, Nicholas J. Davison, Rob Deaville, Matthew Perkins, Susan Jobling, Paul D. Jepson

*Corresponding author for this work

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Abstract

Polychlorinated biphenyls (PCBs) are a group of 209 persistent and bio-accumulative toxic pollutants present as complex mixtures in human and animal tissues. Harbor porpoises accumulate some of the highest levels of PCBs because they are long-lived mammals that feed at a high trophic level. Studies typically use the sum of a suite of individual chlorobiphenyl congeners (CBs) to investigate PCBs in wildlife. However, toxic effects and thresholds of CB congeners differ, therefore population health risks of exposure may be under or over-estimated dependent on the congener profiles present. In this study, we found congener profiles varied with age, sex and location, particularly between adult females and juveniles. We found that adult females had the highest proportions of octa-chlorinated congeners whilst juveniles had the highest proportions of tri- and tetra-chlorinated congeners. This is likely to be a consequence of pollutant offloading between mothers and calves during lactation. Analysis of the individual congener toxicities found that juveniles were exposed to a more neurotoxic CB mixture at a time when they were most vulnerable to its effects. These findings are an important contribution towards our understanding of variation in congener profiles and the potential effects and threats of PCB exposure in cetaceans.

Original languageEnglish
Article number134835
JournalScience of the Total Environment
Volume708
Early online date18 Nov 2019
DOIs
Publication statusFirst published - 18 Nov 2019

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porpoise
Polychlorinated Biphenyls
Ports and harbors
Polychlorinated biphenyls
PCB
harbor
Poisons
Mammals
pollutant
lactation
Health risks
cetacean
Complex Mixtures
trophic level
health risk
Toxicity
Animals
mammal
Tissue
toxicity

Keywords

  • Congener profile
  • Harbor porpoises
  • Polychlorinated biphenyls
  • POPs

Cite this

Williams, Rosie S. ; Curnick, David J. ; Barber, Jonathan L. ; Brownlow, Andrew ; Davison, Nicholas J. ; Deaville, Rob ; Perkins, Matthew ; Jobling, Susan ; Jepson, Paul D. / Juvenile harbor porpoises in the UK are exposed to a more neurotoxic mixture of polychlorinated biphenyls than adults. In: Science of the Total Environment. 2020 ; Vol. 708.
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Juvenile harbor porpoises in the UK are exposed to a more neurotoxic mixture of polychlorinated biphenyls than adults. / Williams, Rosie S.; Curnick, David J.; Barber, Jonathan L.; Brownlow, Andrew; Davison, Nicholas J.; Deaville, Rob; Perkins, Matthew; Jobling, Susan; Jepson, Paul D.

In: Science of the Total Environment, Vol. 708, 134835, 15.03.2020.

Research output: Contribution to journalArticle

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