Microalgal bioactive metabolites as promising implements in nutraceuticals and pharmaceuticals: inspiring therapy for health benefits

Manpreet Kaur*, Surekha Bhatia, Urmila Gupta, Eric Decker, Yamini Tak, Manoj Bali, Vijai Kumar Gupta, Rouf Ahmad Dar, Saroj Bala

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)
93 Downloads (Pure)


The rapid increase in global population and shrinkage of agricultural land necessitates the use of cost-effective renewable sources as alternative to excessive resource-demanding agricultural crops. Microalgae seem to be a potential substitute as it rapidly produces large biomass that can serve as a good source of various functional ingredients that are not produced/synthesized inside the human body and high-value nonessential bioactive compounds. Microalgae-derived bioactive metabolites possess various bioactivities including antioxidant, anti-inflammatory, antimicrobial, anti-carcinogenic, anti-hypertensive, anti-lipidemic, and anti-diabetic activities, thereof rapidly elevating their demand as interesting option in pharmaceuticals, nutraceuticals and functional foods industries for developing new products. However, their utilization in these sectors has been limited. This demands more research to explore the functionality of microalgae derived functional ingredients. Therefore, in this review, we intended to furnish up-to-date knowledge on prospects of bioactive metabolites from microalgae, their bioactivities related to health, the process of microalgae cultivation and harvesting, extraction and purification of bioactive metabolites, role as dietary supplements or functional food, their commercial applications in nutritional and pharmaceutical industries and the challenges in this area of research. Graphical abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)903-933
Number of pages31
JournalPhytochemistry Reviews
Issue number4
Early online date14 Jan 2023
Publication statusPrint publication - Aug 2023

Bibliographical note

Funding Information:
This work has been supported by the SERB, FICCI India and Chemical Resources (CHERESO), Panchkula under Prime Minister Research Fellowship Program.

Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Nature B.V.


  • Bioactive metabolites
  • Bioactivities
  • Functional food
  • Microalgae
  • Nutraceutical
  • Pharmaceutical


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