miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium

Yurii S Aulchenko, TI Axenovich, I Mackay, CM van Duijn

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Summary We describe software which calculates a set of linkage disequilibrium statistics, including multiallelic D′ corrected by the bootstrap and permutation. The software also provides a tool for maximum likelihood and least squares estimation and testing of a set of hierarchical hypotheses formulated within the framework of the Malecot model of the decay of linkage disequilibrium with distance. Additionally, the bootstrap approach is used for estimation of the model parameter's confidence intervals and for hypothesis testing. The programs are available from http://www.geneticepi.com/Research/software/software.html
Original languageEnglish
Pages (from-to)372-375
Number of pages4
JournalAnnals of Human Genetics
Volume67
Issue number4
DOIs
Publication statusPrint publication - Jul 2003
Externally publishedYes

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