miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium

Yurii S Aulchenko; TI Axenovich; I Mackay; CM van Duijn

doi:10.1046/j.1469-1809.2003.00041.x

miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium

Yurii S Aulchenko, TI Axenovich, I Mackay, CM van Duijn

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Summary We describe software which calculates a set of linkage disequilibrium statistics, including multiallelic D′ corrected by the bootstrap and permutation. The software also provides a tool for maximum likelihood and least squares estimation and testing of a set of hierarchical hypotheses formulated within the framework of the Malecot model of the decay of linkage disequilibrium with distance. Additionally, the bootstrap approach is used for estimation of the model parameter's confidence intervals and for hypothesis testing. The programs are available from http://www.geneticepi.com/Research/software/software.html

Original language	English
Pages (from-to)	372-375
Number of pages	4
Journal	Annals of Human Genetics
Volume	67
Issue number	4
DOIs	https://doi.org/10.1046/j.1469-1809.2003.00041.x
Publication status	Print publication - Jul 2003
Externally published	Yes

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title = "miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium",

abstract = "Summary We describe software which calculates a set of linkage disequilibrium statistics, including multiallelic D′ corrected by the bootstrap and permutation. The software also provides a tool for maximum likelihood and least squares estimation and testing of a set of hierarchical hypotheses formulated within the framework of the Malecot model of the decay of linkage disequilibrium with distance. Additionally, the bootstrap approach is used for estimation of the model parameter's confidence intervals and for hypothesis testing. The programs are available from http://www.geneticepi.com/Research/software/software.html",

author = "Aulchenko, {Yurii S} and TI Axenovich and I Mackay and {van Duijn}, CM",

year = "2003",

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doi = "10.1046/j.1469-1809.2003.00041.x",

language = "English",

volume = "67",

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journal = "Annals of Human Genetics",

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T1 - miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium

AU - Aulchenko, Yurii S

AU - Axenovich, TI

AU - Mackay, I

AU - van Duijn, CM

PY - 2003/7

Y1 - 2003/7

N2 - Summary We describe software which calculates a set of linkage disequilibrium statistics, including multiallelic D′ corrected by the bootstrap and permutation. The software also provides a tool for maximum likelihood and least squares estimation and testing of a set of hierarchical hypotheses formulated within the framework of the Malecot model of the decay of linkage disequilibrium with distance. Additionally, the bootstrap approach is used for estimation of the model parameter's confidence intervals and for hypothesis testing. The programs are available from http://www.geneticepi.com/Research/software/software.html

AB - Summary We describe software which calculates a set of linkage disequilibrium statistics, including multiallelic D′ corrected by the bootstrap and permutation. The software also provides a tool for maximum likelihood and least squares estimation and testing of a set of hierarchical hypotheses formulated within the framework of the Malecot model of the decay of linkage disequilibrium with distance. Additionally, the bootstrap approach is used for estimation of the model parameter's confidence intervals and for hypothesis testing. The programs are available from http://www.geneticepi.com/Research/software/software.html

UR - http://www.mendeley.com/research/mild-boold-programs-calculation-analysis-corrected-linkage-disequilibrium

U2 - 10.1046/j.1469-1809.2003.00041.x

DO - 10.1046/j.1469-1809.2003.00041.x

M3 - Article

SN - 0003-4800

VL - 67

SP - 372

EP - 375

JO - Annals of Human Genetics

JF - Annals of Human Genetics

IS - 4

ER -

miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium

Abstract

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