Modelling the impact of vaccination on tuberculosis in badgers

JL Hardstaff, MT Bulling, G Marion, MR Hutchings, PCL White

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Tuberculosis (TB) in livestock, caused by Mycobacterium bovis, persists in many countries. In the UK and Ireland, efforts to control TB through culling of badgers (Meles meles), the principal wildlife host, have failed and there is significant interest in vaccination of badgers as an alternative or complementary strategy. Using a simulation model, we show that where TB is self-contained within the badger population and there are no external sources of infection, limited-duration vaccination at a high level of efficacy can reduce or even eradicate TB from the badger population. However, where sources of external infection persist, benefits in TB reduction in badgers can only be achieved by ongoing, annual vaccination. Vaccination is likely to be most effective as part of an integrated disease management strategy incorporating a number of different approaches across the entire host community.
Original languageEnglish
Pages (from-to)1417 - 1427
Number of pages11
JournalEpidemiology and Infection
Volume141
Issue number7
DOIs
Publication statusPrint publication - 2013

Keywords

  • Mycobacteria
  • Spatial modelling
  • Tuberculosis (TB)
  • Vaccine policy development
  • Zoonoses

Fingerprint Dive into the research topics of 'Modelling the impact of vaccination on tuberculosis in badgers'. Together they form a unique fingerprint.

  • Cite this