Modelling the vector pathway and infection of humans in an environmental outbreak of Escherichia coli O157

Norval J.C. Strachan; David R. Fenlon; Iain D. Ogden

doi:10.1016/S0378-1097(01)00342-1

Modelling the vector pathway and infection of humans in an environmental outbreak of Escherichia coli O157

Norval J.C. Strachan^*, David R. Fenlon, Iain D. Ogden

^*Corresponding author for this work

Veterinary Services

Research output: Contribution to journal › Article › peer-review

89 Citations (Scopus)

Abstract

Quantifying the transfer of Escherichia coli O157 from the environment to humans is essential for understanding outbreaks, establishing the infectious dose of the organism and proposing safeguards. We modelled the pathogen loading shed onto a field by sheep immediately prior to a scout camp where 18 scouts and two adults were infected with E. coli O157. We estimated the dose ingested (4-24 organisms) which is in agreement with the low infective dose reported previously for this organism in food outbreaks. These data closely fit a surrogate Shigella dose-response model which can be used as a basis for risk assessment.

Original language	English
Pages (from-to)	69-73
Number of pages	5
Journal	FEMS Microbiology Letters
Volume	203
Issue number	1
DOIs	https://doi.org/10.1016/S0378-1097(01)00342-1
Publication status	Print publication - 11 Sept 2001

Keywords

Bacterial modelling
Environmental outbreak
Escherichia coli O157

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10.1016/S0378-1097(01)00342-1

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Modelling the vector pathway and infection of humans in an environmental outbreak of Escherichia coli O157

Abstract

Keywords

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