MXene-Based Nanomaterials for Biomedical Applications: Healthier Substitute Materials for the Future

Samarjeet Singh Siwal, Harjot Kaur, Gunjan Chauhan, Vijay Kumar Thakur*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)
82 Downloads (Pure)


MXene-based nanomaterial is a revolution 2D material achieving outstanding scientific attention owing to its universal characteristics for different applications (such as electronic appliances, power production, sensors, drug transfer, and biomedical). Although, the cytotoxic consequences of MXene have a considerable circumstance. Thus, rigorous investigation of the biocompatibility of MXene is a crucial prerequisite, formerly the preface to the human biological approach. Literature reveals functional outcomes wherever MXenes are used in vitro and in vivo cancer representatives. It affects drug transfer methods, sensoring electrodes, and assisting mechanisms for photothermal treatment and hyperthermy techniques. In this review, the synthesis process (such as top-down and bottom-up approaches) and properties (such as mechanical, electrical, optical, oxidative/thermal stability, and magnetic) of MXene-based nanomaterials (NMs) are discussed. In addition, the different applications (such as tissue engineering, cancer theranostic, and other biomedical [such as drug delivery biosensors and surface-enhanced Raman spectroscopy substrates for biomedical applications], antiviral, and immunomodulatory properties against SARS-CoV-2) of MXene-based NMs are discussed in detail. Finally, the conclusion, existing challenges, and future outlooks are highlighted for more scope in this field.
Original languageEnglish
Article number2200123
JournalAdvanced NanoBiomed Research
Issue number1
Early online date4 Dec 2022
Publication statusPrint publication - Jan 2023


  • Biosensors
  • cancer theranostics
  • drug delivery
  • MXene-based nanomterials
  • tissue engineering
  • biosensors
  • MXene-based nanomaterials


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