Novel picornavirus in lambs with severe encephalomyelitis

Leonie F Forth, Sandra F E Scholes, Patricia A Pesavento, Kenneth Jackson, Adrienne Mackintosh, Amanda Carson, Fiona Howie, Kore Schlottau, Kerstin Wernike, Anne Pohlmann, Dirk Höper, Martin Beer*

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Downloads (Pure)

Abstract

Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom. In situ hybridization demonstrated intralesional neuronotropism of this virus, which was also detected in archived samples of similarly affected lambs (1998-2014).

Original languageEnglish
Pages (from-to)963-967
Number of pages5
JournalEmerging Infectious Diseases
Volume25
Issue number5
Early online date18 Apr 2019
DOIs
Publication statusPrint publication - May 2019

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Picornaviridae
Encephalomyelitis
Metagenomics
Encephalitis
Neurologic Manifestations
In Situ Hybridization
Viruses
United Kingdom

Cite this

Forth, L. F., Scholes, S. F. E., Pesavento, P. A., Jackson, K., Mackintosh, A., Carson, A., ... Beer, M. (2019). Novel picornavirus in lambs with severe encephalomyelitis. Emerging Infectious Diseases, 25(5), 963-967. https://doi.org/10.3201/eid2505.181573
Forth, Leonie F ; Scholes, Sandra F E ; Pesavento, Patricia A ; Jackson, Kenneth ; Mackintosh, Adrienne ; Carson, Amanda ; Howie, Fiona ; Schlottau, Kore ; Wernike, Kerstin ; Pohlmann, Anne ; Höper, Dirk ; Beer, Martin. / Novel picornavirus in lambs with severe encephalomyelitis. In: Emerging Infectious Diseases. 2019 ; Vol. 25, No. 5. pp. 963-967.
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Forth, LF, Scholes, SFE, Pesavento, PA, Jackson, K, Mackintosh, A, Carson, A, Howie, F, Schlottau, K, Wernike, K, Pohlmann, A, Höper, D & Beer, M 2019, 'Novel picornavirus in lambs with severe encephalomyelitis', Emerging Infectious Diseases, vol. 25, no. 5, pp. 963-967. https://doi.org/10.3201/eid2505.181573

Novel picornavirus in lambs with severe encephalomyelitis. / Forth, Leonie F; Scholes, Sandra F E; Pesavento, Patricia A; Jackson, Kenneth; Mackintosh, Adrienne; Carson, Amanda; Howie, Fiona; Schlottau, Kore; Wernike, Kerstin; Pohlmann, Anne; Höper, Dirk; Beer, Martin.

In: Emerging Infectious Diseases, Vol. 25, No. 5, 05.2019, p. 963-967.

Research output: Contribution to journalArticle

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AU - Scholes, Sandra F E

AU - Pesavento, Patricia A

AU - Jackson, Kenneth

AU - Mackintosh, Adrienne

AU - Carson, Amanda

AU - Howie, Fiona

AU - Schlottau, Kore

AU - Wernike, Kerstin

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AU - Höper, Dirk

AU - Beer, Martin

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DO - 10.3201/eid2505.181573

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VL - 25

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Forth LF, Scholes SFE, Pesavento PA, Jackson K, Mackintosh A, Carson A et al. Novel picornavirus in lambs with severe encephalomyelitis. Emerging Infectious Diseases. 2019 May;25(5):963-967. https://doi.org/10.3201/eid2505.181573