Recent Advances in the Genomic Resources for Sheep

Shernae Wooley, M Salavati, Emily L Clark*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Abstract

Sheep (Ovis aries) provide a vital source of protein and fibre to human populations. In coming decades, as the pressures associated with rapidly changing climates increase, breeding sheep sustainably as well as producing enough protein to feed a growing human population will pose a considerable challenge for sheep production across the globe. High quality reference genomes and other genomic resources can help to meet these challenges by: 1) informing breeding programmes by adding a priori information about the genome, 2) providing tools such as pangenomes for characterising and conserving global genetic diversity, and 3) improving our understanding of fundamental biology using the power of genomic information to link cell, tissue and whole animal scale knowledge. In this review we describe recent advances in the genomic resources available for sheep, discuss how these might help to meet future challenges for sheep production, and provide some insight into what the future might hold.
Original languageEnglish
Pages (from-to)545-558
Number of pages14
JournalMammalian Genome
Volume34
Issue number4
Early online date26 Sept 2023
DOIs
Publication statusPrint publication - Dec 2023

Keywords

  • sheep
  • genome
  • transcriptome
  • pangenome
  • gene editing
  • Sheep/genetics
  • Animals
  • Genomics
  • Humans
  • Genome

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