Role of Silver Nanoparticle-Doped 2-Aminodiphenylamine Polymeric Material in the Detection of Dopamine (DA) with Uric Acid Interference

Harjot Kaur, Karamveer Sheoran, Samarjeet Singh Siwal*, Reena V. Saini, Adesh Kumar Saini, Walaa F. Alsanie, Vijay Kumar Thakur*

*Corresponding author for this work

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Abstract

A viable electrochemical approach for the detection of dopamine (DA) in uric acid (UA) utilizing a silver nanoparticle-doped 2-aminodiphenylamine (AgNPs-2ADPA) electrode was invented. The electrochemical performance of DA showed that the incorporated electrode displayed outstanding electrocatalytic performance to the electrochemical oxidation of DA. In our study, the AgNPs-2ADPA exhibits remarkable catalytic activity, retaining high current value and resilience when employed as a working electrode component for electrocatalytic detection of DA. We have also utilized the bare and polymeric-2ADPA in DA detection for a comparison study. This method offers a facile route with extraordinary sensitivity, selectivity, and strength for the voltammetric detection of DA, even in the presence of UA and ascorbic acid (AA) as interferents, that can be employed for pharmaceutical and biological specimens.
Original languageEnglish
Article number1308
JournalMaterials
Volume15
Issue number4
Early online date10 Feb 2022
DOIs
Publication statusFirst published - 10 Feb 2022

Keywords

  • Cyclic voltammetry
  • Dopamine
  • Electrochemical methods
  • Silver nanoparticles
  • Uric acid

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