TY - JOUR
T1 - Use of carbohydrate-directed enzymes for the potential exploitation of sugarcane bagasse to obtain value-added biotechnological products
AU - Antoniêto, Amanda Cristina Campos
AU - Nogueira, Karoline Maria Vieira
AU - Mendes, Vanessa
AU - Maués, David Batista
AU - Oshiquiri, Letícia Harumi
AU - Zenaide-Neto, Hermano
AU - de Paula, Renato Graciano
AU - Gaffey, James
AU - Tabatabaei, Meisam
AU - Gupta, Vijai Kumar
AU - Silva, Roberto Nascimento
N1 - Copyright © 2022 Elsevier B.V. All rights reserved.
PY - 2022/11/30
Y1 - 2022/11/30
N2 - Microorganisms, such as fungi and bacteria, are crucial players in the production of enzymatic cocktails for biomass hydrolysis or the bioconversion of plant biomass into products with industrial relevance. The biotechnology industry can exploit lignocellulosic biomass for the production of high-value chemicals. The generation of biotechnological products from lignocellulosic feedstock presents several bottlenecks, including low efficiency of enzymatic hydrolysis, high cost of enzymes, and limitations on microbe metabolic performance. Genetic engineering offers a route for developing improved microbial strains for biotechnological applications in high-value product biosynthesis. Sugarcane bagasse, for example, is an agro-industrial waste that is abundantly produced in sugar and first-generation processing plants. Here, we review the potential conversion of its feedstock into relevant industrial products via microbial production and discuss the advances that have been made in improving strains for biotechnological applications.
AB - Microorganisms, such as fungi and bacteria, are crucial players in the production of enzymatic cocktails for biomass hydrolysis or the bioconversion of plant biomass into products with industrial relevance. The biotechnology industry can exploit lignocellulosic biomass for the production of high-value chemicals. The generation of biotechnological products from lignocellulosic feedstock presents several bottlenecks, including low efficiency of enzymatic hydrolysis, high cost of enzymes, and limitations on microbe metabolic performance. Genetic engineering offers a route for developing improved microbial strains for biotechnological applications in high-value product biosynthesis. Sugarcane bagasse, for example, is an agro-industrial waste that is abundantly produced in sugar and first-generation processing plants. Here, we review the potential conversion of its feedstock into relevant industrial products via microbial production and discuss the advances that have been made in improving strains for biotechnological applications.
KW - CRISPR/Cas
KW - High-value chemicals
KW - Lignocellulosic feedstock
KW - Metabolic engineering
KW - Sugarcane bagasse
UR - http://www.scopus.com/inward/record.url?scp=85137626567&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2022.08.186
DO - 10.1016/j.ijbiomac.2022.08.186
M3 - Review article
C2 - 36070819
AN - SCOPUS:85137626567
SN - 0141-8130
VL - 221
SP - 456
EP - 471
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
ER -