TY - JOUR
T1 - Vasoactive intestinal peptide (VIP)
T2 - Historic perspective and future potential
AU - Foster, Neil
PY - 2012/12/3
Y1 - 2012/12/3
N2 - Numerous studies, since the late 1970s, have highlighted the role of vasoactive intestinal peptide (VIP) in the immune system of mammals. Importantly, these studies have show that VIP has an inhibitory effect on the production and action of many different inflammatory mediators and many studies have now shown the therapeutic potential of VIP in animal models of human disease. This review will briefly discuss the effects of VIP on immune cell function and discuss the therapeutic potential for VIP in inflammatory diseases of humans. The review will also introduce some areas of research which are discussed by contributing authors within this special edition of EMIDDT.
AB - Numerous studies, since the late 1970s, have highlighted the role of vasoactive intestinal peptide (VIP) in the immune system of mammals. Importantly, these studies have show that VIP has an inhibitory effect on the production and action of many different inflammatory mediators and many studies have now shown the therapeutic potential of VIP in animal models of human disease. This review will briefly discuss the effects of VIP on immune cell function and discuss the therapeutic potential for VIP in inflammatory diseases of humans. The review will also introduce some areas of research which are discussed by contributing authors within this special edition of EMIDDT.
UR - http://www.scopus.com/inward/record.url?scp=84870164025&partnerID=8YFLogxK
U2 - 10.2174/187153012803832521
DO - 10.2174/187153012803832521
M3 - Editorial
C2 - 23094826
AN - SCOPUS:84870164025
SN - 1871-5303
VL - 12
SP - 303
EP - 307
JO - Endocrine, Metabolic and Immune Disorders - Drug Targets
JF - Endocrine, Metabolic and Immune Disorders - Drug Targets
IS - 4
ER -