Whole genome sequences of 70 indigenous Ethiopian cattle

Wondossen Ayalew, Wu Xiaoyun, Getinet Mekuriaw Tarekegn, Rakan Naboulsi, Tesfaye Sisay Tessema, Renaud Van Damme, Erik Bongcam-Rudloff, Min Chu, Chunnian Liang, Zewdu Edea, Solomon Enquahone, Yan Ping

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Abstract

Indigenous animal genetic resources play a crucial role in preserving global genetic diversity and supporting the livelihoods of millions of people. In Ethiopia, the majority of the cattle population consists of indigenous breeds. Understanding the genetic architecture of these cattle breeds is essential for effective management and conservation efforts. In this study, we sequenced DNA samples from 70 animals from seven indigenous cattle breeds, generating about two terabytes of pair-end reads with an average coverage of 14X. The sequencing data were pre-processed and mapped to the cattle reference genome (ARS-UCD1.2) with an alignment rate of 99.2%. Finally, the variant calling process produced approximately 35 million high-quality SNPs. These data provide a deeper understanding of the genetic landscape, facilitate the identification of causal mutations, and enable the exploration of evolutionary patterns to assist cattle improvement and sustainable utilization, particularly in the face of unpredictable climate changes.

Original languageEnglish
Article number584
JournalScientific data
Volume11
Issue number1
Early online date5 Jun 2024
DOIs
Publication statusFirst published - 5 Jun 2024

Bibliographical note

Publisher Copyright:
© The Author(s) 2024.

Keywords

  • Animals
  • Cattle/genetics
  • Breeding
  • Ethiopia
  • Genome
  • Polymorphism, Single Nucleotide
  • Whole Genome Sequencing

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